miRNA description for miR-146a-5p
miRNA accession miR-146a-5p
Species Homo sapiens
 miR-146a-5p identified in exosomes derived from the following tissue/cell type
Colorectal cancer cells [Exosomes] 35443745   
Colorectal cancer cells [Exosomes] 35443745   
Mesenchymal stem cells [Exosomes] 33479185   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Plasma [Extracellular vesicles/Exosomes] 31762962   
Pulmonary artery endothelial cells [Exosomes] 32132543   
Pulmonary artery endothelial cells [Exosomes] 32132543   
 Experiment description of studies that identified miR-146a-5p in exosomes
1
Experiment ID2612
Identified moleculemiRNA
Identification method RT-qPCR
PubMed ID 35443745   
OrganismHomo sapiens
Experiment descriptionExosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts
AuthorsWang D, Wang X, Song Y, Si M, Sun Y, Liu X, Cui S, Qu X, Yu X.
Journal name Cell Death Dis
Publication year2022
SampleColorectal cancer cells
Sample nameHCT116
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
RNA sequencing
RT-qPCR
EV-TRACK -
2
Experiment ID2613
Identified moleculemiRNA
Identification method RT-qPCR
PubMed ID 35443745   
OrganismHomo sapiens
Experiment descriptionExosomal miR-146a-5p and miR-155-5p promote CXCL12/CXCR7-induced metastasis of colorectal cancer by crosstalk with cancer-associated fibroblasts
AuthorsWang D, Wang X, Song Y, Si M, Sun Y, Liu X, Cui S, Qu X, Yu X.
Journal name Cell Death Dis
Publication year2022
SampleColorectal cancer cells
Sample nameHCT116
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
RNA sequencing
RT-qPCR
EV-TRACK -
3
Experiment ID1526
Identified moleculemiRNA
Identification method Microarray
PubMed ID 33479185   
OrganismHomo sapiens
Experiment descriptionHuman umbilical cord mesenchymal stem cell-derived exosomal miR-146a-5p reduces microglial-mediated neuroinflammation via suppression of the IRAK1/TRAF6 signaling pathway after ischemic stroke
AuthorsZhang Z, Zou X, Zhang R, Xie Y, Feng Z, Li F, Han J, Sun H, Ouyang Q, Hua S, Lv B, Hua T, Liu Z, Cai Y, Zou Y, Tang Y, Jiang X.
Journal name Aging
Publication year2021
SampleMesenchymal stem cells
Sample namehUMSCs
Molecules identified in the studyProtein
miRNA
Methods used in the studyWestern blotting
Microarray
EV-TRACK -
4
Experiment ID2317
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameNon-smokers
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
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5
Experiment ID2318
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameSmokers
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -
6
Experiment ID2319
Identified moleculemiRNA
Identification method Small RNA sequencing
PubMed ID 31762962   
OrganismHomo sapiens
Experiment descriptionSmall RNA-sequence analysis of plasma-derived extracellular vesicle miRNAs in smokers and patients with chronic obstructive pulmonary disease as circulating biomarkers
AuthorsSundar IK, Li D, Rahman I.
Journal name J Extracell Vesicles
Publication year2019
SamplePlasma
Sample nameCOPD patients
Molecules identified in the studyProtein
small RNA
Methods used in the studyWestern blotting
Small RNA sequencing
EV-TRACK -
7
Experiment ID1468
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 32132543   
OrganismHomo sapiens
Experiment descriptionTherapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
AuthorsSindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B.
Journal name Nat Commun
Publication year2020
SamplePulmonary artery endothelial cells
Sample nameHPAEC
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
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8
Experiment ID1469
Identified moleculemiRNA
Identification method RT-PCR
PubMed ID 32132543   
OrganismHomo sapiens
Experiment descriptionTherapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension
AuthorsSindi HA, Russomanno G, Satta S, Abdul-Salam VB, Jo KB, Qazi-Chaudhry B, Ainscough AJ, Szulcek R, Jan Bogaard H, Morgan CC, Pullamsetti SS, Alzaydi MM, Rhodes CJ, Piva R, Eichstaedt CA, Grünig E, Wilkins MR, Wojciak-Stothard B.
Journal name Nat Commun
Publication year2020
SamplePulmonary artery endothelial cells
Sample nameHPAEC
Molecules identified in the studymiRNA
Methods used in the studyRT-PCR
EV-TRACK -